A synthetic methylotroph achieves accelerated cell growth by alleviating transcription-replication conflicts

Abstract Microbial utilization of methanol for valorization is an effective way to advance green bio-manufacturing technology. Although synthetic methylotrophs have been developed, strategies to enhance their cell growth rate and internal regulatory mechanism remain underexplored. In this study, we...

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Bibliographic Details
Main Authors: Xin Meng, Guipeng Hu, Xiaomin Li, Cong Gao, Wei Song, Wanqing Wei, Jing Wu, Liming Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55502-5
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