Microglia TRPC1 SUMOylation drives neuroinflammation after stroke by modulating NLRP3 activity via increasing TRPC1 interaction with ARRB2
Microglial canonical transient receptor potential channel 1 (TRPC1) has been proposed to influence neuroinflammation after cerebral ischemia and reperfusion injury (CIRI), however, the underlying mechanism remains poorly understood. This study demonstrates that TRPC1 is modified by small ubiquitin-r...
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Main Authors: | Huinan Zhang, Xinzhe Du, Tian Gao, Xing Wang, Huifeng Zhang, Manyang Yu, Jing Huang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-03-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S096999612500049X |
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