Randomized Control Trial for Reduction of Body Weight, Body Fat Patterning, and Cardiometabolic Risk Factors in Overweight Worksite Employees in Delhi, India

Background. We studied the impact of the multicomponent interventions on body weight and cardiometabolic risk factors in overweight individuals working in corporate worksites. Methods. Overweight (BMI ≥ 23 kg/m2) subjects were recruited from four randomised worksites [two active intervention (n, rec...

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Main Authors: Usha Shrivastava, Mahrukh Fatma, Smriti Mohan, Padam Singh, Anoop Misra
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2017/7254174
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author Usha Shrivastava
Mahrukh Fatma
Smriti Mohan
Padam Singh
Anoop Misra
author_facet Usha Shrivastava
Mahrukh Fatma
Smriti Mohan
Padam Singh
Anoop Misra
author_sort Usha Shrivastava
collection DOAJ
description Background. We studied the impact of the multicomponent interventions on body weight and cardiometabolic risk factors in overweight individuals working in corporate worksites. Methods. Overweight (BMI ≥ 23 kg/m2) subjects were recruited from four randomised worksites [two active intervention (n, recruited, 180, completed 156) and two control (n, recruited 130, completed 111)]. Intensive intervention was given at intervention worksite. Results. High prevalence (%) of obesity (90.9, 80.2), abdominal obesity (93.5, 84.3), excess skinfold thickness (70.3, 75.9), and low high-density lipoprotein cholesterol (HDL-c) levels (56.8, 63.7) were seen in the intervention and the control group, respectively. At the end of intervention, the following significant changes were observed in the intervention group: decrease in weight, BMI, waist circumference, serum triglycerides, and increase in HDL-c. Weight loss of more than 5% was seen in 12% and 4% individuals in the intervention and control groups, respectively. Most importantly, the sum of all the skinfold measurements (mm) in the intervention group decreased significantly more than the control group (12.51 ± 10.38 versus 3.50 ± 8.18, resp.). Conclusion. This multicomponent worksite trial showed a reduction in weight, excess subcutaneous fat, and cardiometabolic risk factors after 6 months of active intervention in overweight Asian Indians. Trial Registration. This trial is registered with NCT03249610.
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spelling doaj-art-ce180f6f9f1c4554b7bae237030aadd42025-02-03T01:07:23ZengWileyJournal of Diabetes Research2314-67452314-67532017-01-01201710.1155/2017/72541747254174Randomized Control Trial for Reduction of Body Weight, Body Fat Patterning, and Cardiometabolic Risk Factors in Overweight Worksite Employees in Delhi, IndiaUsha Shrivastava0Mahrukh Fatma1Smriti Mohan2Padam Singh3Anoop Misra4National Diabetes, Obesity and Cholesterol Foundation, New Delhi, IndiaNational Diabetes, Obesity and Cholesterol Foundation, New Delhi, IndiaNational Diabetes, Obesity and Cholesterol Foundation, New Delhi, IndiaFortis C-DOC Hospital for Diabetes, Metabolic Diseases and Endocrinology, New Delhi, IndiaNational Diabetes, Obesity and Cholesterol Foundation, New Delhi, IndiaBackground. We studied the impact of the multicomponent interventions on body weight and cardiometabolic risk factors in overweight individuals working in corporate worksites. Methods. Overweight (BMI ≥ 23 kg/m2) subjects were recruited from four randomised worksites [two active intervention (n, recruited, 180, completed 156) and two control (n, recruited 130, completed 111)]. Intensive intervention was given at intervention worksite. Results. High prevalence (%) of obesity (90.9, 80.2), abdominal obesity (93.5, 84.3), excess skinfold thickness (70.3, 75.9), and low high-density lipoprotein cholesterol (HDL-c) levels (56.8, 63.7) were seen in the intervention and the control group, respectively. At the end of intervention, the following significant changes were observed in the intervention group: decrease in weight, BMI, waist circumference, serum triglycerides, and increase in HDL-c. Weight loss of more than 5% was seen in 12% and 4% individuals in the intervention and control groups, respectively. Most importantly, the sum of all the skinfold measurements (mm) in the intervention group decreased significantly more than the control group (12.51 ± 10.38 versus 3.50 ± 8.18, resp.). Conclusion. This multicomponent worksite trial showed a reduction in weight, excess subcutaneous fat, and cardiometabolic risk factors after 6 months of active intervention in overweight Asian Indians. Trial Registration. This trial is registered with NCT03249610.http://dx.doi.org/10.1155/2017/7254174
spellingShingle Usha Shrivastava
Mahrukh Fatma
Smriti Mohan
Padam Singh
Anoop Misra
Randomized Control Trial for Reduction of Body Weight, Body Fat Patterning, and Cardiometabolic Risk Factors in Overweight Worksite Employees in Delhi, India
Journal of Diabetes Research
title Randomized Control Trial for Reduction of Body Weight, Body Fat Patterning, and Cardiometabolic Risk Factors in Overweight Worksite Employees in Delhi, India
title_full Randomized Control Trial for Reduction of Body Weight, Body Fat Patterning, and Cardiometabolic Risk Factors in Overweight Worksite Employees in Delhi, India
title_fullStr Randomized Control Trial for Reduction of Body Weight, Body Fat Patterning, and Cardiometabolic Risk Factors in Overweight Worksite Employees in Delhi, India
title_full_unstemmed Randomized Control Trial for Reduction of Body Weight, Body Fat Patterning, and Cardiometabolic Risk Factors in Overweight Worksite Employees in Delhi, India
title_short Randomized Control Trial for Reduction of Body Weight, Body Fat Patterning, and Cardiometabolic Risk Factors in Overweight Worksite Employees in Delhi, India
title_sort randomized control trial for reduction of body weight body fat patterning and cardiometabolic risk factors in overweight worksite employees in delhi india
url http://dx.doi.org/10.1155/2017/7254174
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