Using β-Elemene to reduce stemness and drug resistance in osteosarcoma: A focus on the AKT/FOXO1 signaling pathway and immune modulation

Objective: Osteosarcoma, a highly malignant bone tumor, poses significant treatment challenges due to its propensity for stemness and drug resistance, particularly against doxorubicin (DOX). This study aims to investigate the mechanism by which β-elemene reduces the stemness of osteosarcoma stem cel...

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Bibliographic Details
Main Authors: Shaochun Zhang, Zhijie Xing, Jing Ke
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Journal of Bone Oncology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2212137424001350
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