Could the Microbial Profiling of Normal Pancreatic Tissue from Healthy Organ Donors Contribute to Understanding the Intratumoral Microbiota Signature in Pancreatic Ductal Adenocarcinoma?

Could the Microbial Profiling of Normal Pancreatic Tissue from Healthy Organ Donors Contribute to Understanding the Intratumoral Microbiota Signature in Pancreatic Ductal Adenocarcinoma?

Pancreatic ductal adenocarcinoma (PDAC) is associated with intratumoral microbiota changes. However, defining the normal pancreatic microbial composition remains a challenge. Herein, we tested the hypothesis that the microbial profiling of normal pancreatic tissue from healthy organ donors (HC) coul...

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Bibliographic Details
Main Authors: Francesca Tavano, Alessandro Napoli, Domenica Gioffreda, Orazio Palmieri, Tiziana Latiano, Matteo Tardio, Fabio Francesco di Mola, Tommaso Grottola, Markus W. Büchler, Marco Gentile, Anna Latiano, Tommaso Mazza, Francesco Perri
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Microorganisms
Subjects:
pancreatic ductal adenocarcinoma
microbiota
intratumoral bacteria
tumor microenvironment
16S rRNA gene sequencing
carcinogenesis
Online Access:https://www.mdpi.com/2076-2607/13/2/452
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