Neural Blockade in the Evaluation and Management of Chronic Pain: An Overview
Local anesthetic and neurolytic nerve blocks have been used for over a century in the evaluation and management of chronic pain, despite a the dearth of evidence supporting their application. This article provides a general overview of the physiology and pharmacology of nerve blocks and suggests how...
Saved in:
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2000-01-01
|
| Series: | Pain Research and Management |
| Online Access: | http://dx.doi.org/10.1155/2000/546792 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832551632324263936 |
|---|---|
| author | Ian Gilron |
| author_facet | Ian Gilron |
| author_sort | Ian Gilron |
| collection | DOAJ |
| description | Local anesthetic and neurolytic nerve blocks have been used for over a century in the evaluation and management of chronic pain, despite a the dearth of evidence supporting their application. This article provides a general overview of the physiology and pharmacology of nerve blocks and suggests how they may affect pathophysiological mechanisms of chronic pain. Following a discussion of the rationale, clinical application and potential complications of nerve blocks, existing evidence of efficacy is reviewed. Further research evaluating mechanisms and efficacy of nerve blocks is vital to define their role in chronic pain management. |
| format | Article |
| id | doaj-art-cdcc4a048ddc44ac80d8aefd9cb08e6c |
| institution | Kabale University |
| issn | 1203-6765 |
| language | English |
| publishDate | 2000-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pain Research and Management |
| spelling | doaj-art-cdcc4a048ddc44ac80d8aefd9cb08e6c2025-02-03T06:01:06ZengWileyPain Research and Management1203-67652000-01-01519310010.1155/2000/546792Neural Blockade in the Evaluation and Management of Chronic Pain: An OverviewIan Gilron0Pain and Neurosensory Mechanisms Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USALocal anesthetic and neurolytic nerve blocks have been used for over a century in the evaluation and management of chronic pain, despite a the dearth of evidence supporting their application. This article provides a general overview of the physiology and pharmacology of nerve blocks and suggests how they may affect pathophysiological mechanisms of chronic pain. Following a discussion of the rationale, clinical application and potential complications of nerve blocks, existing evidence of efficacy is reviewed. Further research evaluating mechanisms and efficacy of nerve blocks is vital to define their role in chronic pain management.http://dx.doi.org/10.1155/2000/546792 |
| spellingShingle | Ian Gilron Neural Blockade in the Evaluation and Management of Chronic Pain: An Overview Pain Research and Management |
| title | Neural Blockade in the Evaluation and Management of Chronic Pain: An Overview |
| title_full | Neural Blockade in the Evaluation and Management of Chronic Pain: An Overview |
| title_fullStr | Neural Blockade in the Evaluation and Management of Chronic Pain: An Overview |
| title_full_unstemmed | Neural Blockade in the Evaluation and Management of Chronic Pain: An Overview |
| title_short | Neural Blockade in the Evaluation and Management of Chronic Pain: An Overview |
| title_sort | neural blockade in the evaluation and management of chronic pain an overview |
| url | http://dx.doi.org/10.1155/2000/546792 |
| work_keys_str_mv | AT iangilron neuralblockadeintheevaluationandmanagementofchronicpainanoverview |