Wrist accelerometry and machine learning sensitively capture disease progression in prodromal Parkinson’s disease

Abstract Sensitive motor measures are needed to support trials in Parkinson’s disease (PD). Wrist sensor data was collected continuously at home from 269 individuals with PD (106 with prodromal PD). Submovements were smaller, slower, and less variable in PD and prodromal PD. A machine-learned compos...

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Bibliographic Details
Main Authors: Anoopum S. Gupta, Siddharth Patel
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-01034-8
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