Trem2 regulates microglial migratory responses via type I interferon signaling during photoreceptor degeneration

Abstract Background Various functions of activated microglia play crucial roles in the progression of retinitis pigmentosa (RP). This study aims to investigate the mechanisms underlying microglial migratory responses and phagocytic activity and their effects on photoreceptor degeneration. Methods Tr...

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Bibliographic Details
Main Authors: Jincan He, Wenchuan Zhou, Jing Li
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-025-02261-5
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