Expression of the TIGIT axis and the CD39/CD73 purinergic pathway in bone metastasis-derived immune cells

Expression of the TIGIT axis and the CD39/CD73 purinergic pathway in bone metastasis-derived immune cells

Abstract Background Bone metastases (BM) represent one of the most common sites of metastasis. The study aimed to compare the composition of immune cell infiltration from aspirates of different BM prior to systemic therapy. Method Phenotypic and functional analyses were conducted via multiparametric...

Full description

Saved in:
Bibliographic Details
Main Authors: Elias Brauneck, Leon-Gordian Leonhardt, Anne Marie Assemissen, Yagana Wahid, Moritz Kruppa, Niklas Kruppa, Julius Krüger, Stephan Menzel, Friedrich Koch-Nolte, Julian Kylies, Katja Weisel, Carsten Bokemeyer, Jasmin Wellbrock, Walter Fiedler, Lennart Viezens, Franziska Brauneck
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Cancer Immunology, Immunotherapy
Subjects:
Bone metastasis
Immune cells
Anti-tumor immunity
Checkpoint molecules
TIGIT axis
Purinergic signaling
Online Access:https://doi.org/10.1007/s00262-025-04030-2
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1007/s00262-025-04030-2

Similar Items