Severe Hypertriglyceridemia Induced Pancreatitis in Pregnancy
Acute pancreatitis caused by severe gestational hypertriglyceridemia is a rare complication of pregnancy. Acute pancreatitis has been well associated with gallstone disease, alcoholism, or drug abuse but rarely seen in association with severe hypertriglyceridemia. Hypertriglyceridemia may occur in p...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2014/485493 |
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| author | Natasha Gupta Seema Ahmed Lemuel Shaffer Paula Cavens Josef Blankstein |
| author_facet | Natasha Gupta Seema Ahmed Lemuel Shaffer Paula Cavens Josef Blankstein |
| author_sort | Natasha Gupta |
| collection | DOAJ |
| description | Acute pancreatitis caused by severe gestational hypertriglyceridemia is a rare complication of pregnancy. Acute pancreatitis has been well associated with gallstone disease, alcoholism, or drug abuse but rarely seen in association with severe hypertriglyceridemia. Hypertriglyceridemia may occur in pregnancy due to normal physiological changes leading to abnormalities in lipid metabolism. We report a case of severe gestational hypertriglyceridemia that caused acute pancreatitis at full term and was successfully treated with postpartum therapeutic plasma exchange. Patient also developed several other complications related to her substantial hypertriglyceridemia including preeclampsia, chylous ascites, retinal detachment, pleural effusion, and chronic pericarditis. This patient had no previous family or personal history of lipid abnormality and had four successful prior pregnancies without developing gestational hypertriglyceridemia. Such a severe hypertriglyceridemia is usually seen in patients with familial chylomicronemia syndromes where hypertriglyceridemia is exacerbated by the pregnancy, leading to fatal complications such as acute pancreatitis. |
| format | Article |
| id | doaj-art-ccf8656fdc7042f3a4a5fb00c5f7c837 |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-ccf8656fdc7042f3a4a5fb00c5f7c8372025-02-03T01:02:57ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922014-01-01201410.1155/2014/485493485493Severe Hypertriglyceridemia Induced Pancreatitis in PregnancyNatasha Gupta0Seema Ahmed1Lemuel Shaffer2Paula Cavens3Josef Blankstein4Department of Obstetrics and Gynecology, Mount Sinai Hospital, 1500 S California Avenue, Chicago, IL 60608, USADepartment of Obstetrics and Gynecology, Mount Sinai Hospital, 1500 S California Avenue, Chicago, IL 60608, USADepartment of Obstetrics and Gynecology, Mount Sinai Hospital, 1500 S California Avenue, Chicago, IL 60608, USADepartment of Obstetrics and Gynecology, Mount Sinai Hospital, 1500 S California Avenue, Chicago, IL 60608, USADepartment of Obstetrics and Gynecology, Mount Sinai Hospital, 1500 S California Avenue, Chicago, IL 60608, USAAcute pancreatitis caused by severe gestational hypertriglyceridemia is a rare complication of pregnancy. Acute pancreatitis has been well associated with gallstone disease, alcoholism, or drug abuse but rarely seen in association with severe hypertriglyceridemia. Hypertriglyceridemia may occur in pregnancy due to normal physiological changes leading to abnormalities in lipid metabolism. We report a case of severe gestational hypertriglyceridemia that caused acute pancreatitis at full term and was successfully treated with postpartum therapeutic plasma exchange. Patient also developed several other complications related to her substantial hypertriglyceridemia including preeclampsia, chylous ascites, retinal detachment, pleural effusion, and chronic pericarditis. This patient had no previous family or personal history of lipid abnormality and had four successful prior pregnancies without developing gestational hypertriglyceridemia. Such a severe hypertriglyceridemia is usually seen in patients with familial chylomicronemia syndromes where hypertriglyceridemia is exacerbated by the pregnancy, leading to fatal complications such as acute pancreatitis.http://dx.doi.org/10.1155/2014/485493 |
| spellingShingle | Natasha Gupta Seema Ahmed Lemuel Shaffer Paula Cavens Josef Blankstein Severe Hypertriglyceridemia Induced Pancreatitis in Pregnancy Case Reports in Obstetrics and Gynecology |
| title | Severe Hypertriglyceridemia Induced Pancreatitis in Pregnancy |
| title_full | Severe Hypertriglyceridemia Induced Pancreatitis in Pregnancy |
| title_fullStr | Severe Hypertriglyceridemia Induced Pancreatitis in Pregnancy |
| title_full_unstemmed | Severe Hypertriglyceridemia Induced Pancreatitis in Pregnancy |
| title_short | Severe Hypertriglyceridemia Induced Pancreatitis in Pregnancy |
| title_sort | severe hypertriglyceridemia induced pancreatitis in pregnancy |
| url | http://dx.doi.org/10.1155/2014/485493 |
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