FDT Perimetry for Glaucoma Detection in Comprehensive Health Checkup Service

We aimed to investigate the efficacy of frequency doubling technology (FDT) perimetry for glaucoma detection in comprehensive screening examinations. We performed a retrospective analysis of prospectively collected data of participants who underwent a comprehensive health checkup service. Participan...

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Main Authors: Ryo Terauchi, Takashi Wada, Shumpei Ogawa, Masanobu Kaji, Tomohiro Kato, Masayuki Tatemichi, Tadashi Nakano
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2020/4687398
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author Ryo Terauchi
Takashi Wada
Shumpei Ogawa
Masanobu Kaji
Tomohiro Kato
Masayuki Tatemichi
Tadashi Nakano
author_facet Ryo Terauchi
Takashi Wada
Shumpei Ogawa
Masanobu Kaji
Tomohiro Kato
Masayuki Tatemichi
Tadashi Nakano
author_sort Ryo Terauchi
collection DOAJ
description We aimed to investigate the efficacy of frequency doubling technology (FDT) perimetry for glaucoma detection in comprehensive screening examinations. We performed a retrospective analysis of prospectively collected data of participants who underwent a comprehensive health checkup service. Participants with glaucoma were excluded. In the first year, 2024 participants (46.8 ± 9.4 years) who underwent FDT perimetry and fundus photography were classified as the FDT group, whereas 3052 participants (42.2 ± 8.2 years) who underwent only fundus photography were classified as the non-FDT control group. Participants with abnormal findings on FDT perimetry and/or fundus photography were recommended to undergo further complete examination. All participants reported whether they had been newly diagnosed with glaucoma within 2 years of the first visit. In the FDT group, 23 (1.14%) participants were newly diagnosed with glaucoma. Among them, 20 (87.0%) had abnormal FDT perimetry findings and 12 (52.2%) had abnormal findings on fundus photography. The positive-predictive value (PPV) of FDT perimetry was 16.5% (20/121) and that of fundus photography was 13.3% (12/90). In participants with abnormal findings on both tests, the PPV was 26.2%. In the non-FDT group, 15 (0.49%) participants were newly diagnosed with glaucoma. Among them, 9 (60.0%) had abnormal findings on fundus photography. The PPV of fundus photography was 10.8% (9/83). The glaucoma detection rate, analyzed using age adjustment, was significantly higher in the FDT group than that in the non-FDT group (0.97% versus 0.47%, P=0.041). FDT perimetry, even if performed by nonspecialized physicians, could improve glaucoma detection when used in addition to fundus photography. This study was registered with UMIN000037951.
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spelling doaj-art-ccefd298ace24fa0b102621e7c50b4f32025-02-03T01:26:25ZengWileyJournal of Ophthalmology2090-004X2090-00582020-01-01202010.1155/2020/46873984687398FDT Perimetry for Glaucoma Detection in Comprehensive Health Checkup ServiceRyo Terauchi0Takashi Wada1Shumpei Ogawa2Masanobu Kaji3Tomohiro Kato4Masayuki Tatemichi5Tadashi Nakano6Department of Ophthalmology, The Jikei University School of Medicine, Tokyo 105-8461, JapanHealth Science, The Jikei University School of Medicine, Tokyo 105-8461, JapanDepartment of Ophthalmology, The Jikei University School of Medicine, Tokyo 105-8461, JapanHarumi Toriton Clinic, The Jikei University School of Medicine, Tokyo 104-0053, JapanCenter for Preventive Medicine, The Jikei University School of Medicine, Tokyo 105-8461, JapanDepartment of Preventive Medicine, Tokai University School of Medicine, Isehara 259-1193, JapanDepartment of Ophthalmology, The Jikei University School of Medicine, Tokyo 105-8461, JapanWe aimed to investigate the efficacy of frequency doubling technology (FDT) perimetry for glaucoma detection in comprehensive screening examinations. We performed a retrospective analysis of prospectively collected data of participants who underwent a comprehensive health checkup service. Participants with glaucoma were excluded. In the first year, 2024 participants (46.8 ± 9.4 years) who underwent FDT perimetry and fundus photography were classified as the FDT group, whereas 3052 participants (42.2 ± 8.2 years) who underwent only fundus photography were classified as the non-FDT control group. Participants with abnormal findings on FDT perimetry and/or fundus photography were recommended to undergo further complete examination. All participants reported whether they had been newly diagnosed with glaucoma within 2 years of the first visit. In the FDT group, 23 (1.14%) participants were newly diagnosed with glaucoma. Among them, 20 (87.0%) had abnormal FDT perimetry findings and 12 (52.2%) had abnormal findings on fundus photography. The positive-predictive value (PPV) of FDT perimetry was 16.5% (20/121) and that of fundus photography was 13.3% (12/90). In participants with abnormal findings on both tests, the PPV was 26.2%. In the non-FDT group, 15 (0.49%) participants were newly diagnosed with glaucoma. Among them, 9 (60.0%) had abnormal findings on fundus photography. The PPV of fundus photography was 10.8% (9/83). The glaucoma detection rate, analyzed using age adjustment, was significantly higher in the FDT group than that in the non-FDT group (0.97% versus 0.47%, P=0.041). FDT perimetry, even if performed by nonspecialized physicians, could improve glaucoma detection when used in addition to fundus photography. This study was registered with UMIN000037951.http://dx.doi.org/10.1155/2020/4687398
spellingShingle Ryo Terauchi
Takashi Wada
Shumpei Ogawa
Masanobu Kaji
Tomohiro Kato
Masayuki Tatemichi
Tadashi Nakano
FDT Perimetry for Glaucoma Detection in Comprehensive Health Checkup Service
Journal of Ophthalmology
title FDT Perimetry for Glaucoma Detection in Comprehensive Health Checkup Service
title_full FDT Perimetry for Glaucoma Detection in Comprehensive Health Checkup Service
title_fullStr FDT Perimetry for Glaucoma Detection in Comprehensive Health Checkup Service
title_full_unstemmed FDT Perimetry for Glaucoma Detection in Comprehensive Health Checkup Service
title_short FDT Perimetry for Glaucoma Detection in Comprehensive Health Checkup Service
title_sort fdt perimetry for glaucoma detection in comprehensive health checkup service
url http://dx.doi.org/10.1155/2020/4687398
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