Mild Hypothermia Attenuates Intercellular Adhesion Molecule-1 Induction via Activation of Extracellular Signal-Regulated Kinase-1/2 in a Focal Cerebral Ischemia Model

Mild Hypothermia Attenuates Intercellular Adhesion Molecule-1 Induction via Activation of Extracellular Signal-Regulated Kinase-1/2 in a Focal Cerebral Ischemia Model

Intercellular adhesion molecule-1 (ICAM-1) in cerebral vascular endothelium induced by ischemic insult triggers leukocyte infiltration and inflammatory reaction. We investigated the mechanism of hypothermic suppression of ICAM-1 in a model of focal cerebral ischemia. Rats underwent 2 hours of middle...

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Bibliographic Details
Main Authors:	Jung Sook Choi, Jaechan Park, Kyoungho Suk, Cheil Moon, Yong-Ki Park, Hyung Soo Han
Format:	Article
Language:	English
Published:	Wiley 2011-01-01
Series:	Stroke Research and Treatment
Online Access:	http://dx.doi.org/10.4061/2011/846716
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