Association of triglyceride-glucose-body mass index with all-cause mortality among individuals with cardiovascular disease: results from NHANES
BackgroundThe objective of this study was to explore the relationship between the triglyceride-glucose-body mass index (TyG-BMI) and all-cause mortality rate and to determine valuable predictive factors for the survival status of patients with cardiovascular disease (CVD).MethodsConduct a study on C...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2025.1529004/full |
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| author | Yiaoran Sun Yiaoran Sun Yuecheng Hu Yuecheng Hu |
| author_facet | Yiaoran Sun Yiaoran Sun Yuecheng Hu Yuecheng Hu |
| author_sort | Yiaoran Sun |
| collection | DOAJ |
| description | BackgroundThe objective of this study was to explore the relationship between the triglyceride-glucose-body mass index (TyG-BMI) and all-cause mortality rate and to determine valuable predictive factors for the survival status of patients with cardiovascular disease (CVD).MethodsConduct a study on CVD patients in the NHANES database from 2007 to 2016. Patients were divided into four groups based on the weighted quartiles of TyG-BMI. Kaplan-Meier curves, Cox regression, and restricted cubic spline (RCS) were used to analyze the correlation between this index and all-cause mortality. Receiver operating characteristic (ROC) curves were used to evaluate its predictive ability, sensitivity, and specificity.ResultsThis study included 1085 patients, and revealed significant differences in survival rates among patients with different TyG-BMI levels. Patients in the higher TyG-BMI group have a lower mortality risk, yet there is no evident non-linear relationship. The ROC curve indicates that this indicator can serve as a predictive value for mortality in CVD patients, demonstrating good sensitivity and specificity.ConclusionThis study found a significant association between TyG-BMI index and all-cause mortality in patients with CVD. TyG-BMI can be used as a predictive indicator of all-cause mortality in CVD patients. |
| format | Article |
| id | doaj-art-ccdbe5a25afb47c2ba2d150c771dbf3c |
| institution | Kabale University |
| issn | 1664-2392 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj-art-ccdbe5a25afb47c2ba2d150c771dbf3c2025-01-27T11:48:14ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922025-01-011610.3389/fendo.2025.15290041529004Association of triglyceride-glucose-body mass index with all-cause mortality among individuals with cardiovascular disease: results from NHANESYiaoran Sun0Yiaoran Sun1Yuecheng Hu2Yuecheng Hu3School of Basic Medicine, Tianjin Medical University, Tianjin, ChinaClinical School of Thoracic, Tianjin Medical University, Tianjin, ChinaClinical School of Thoracic, Tianjin Medical University, Tianjin, ChinaDepartment of Cardiology, Tianjin Chest Hospital, Tianjin, ChinaBackgroundThe objective of this study was to explore the relationship between the triglyceride-glucose-body mass index (TyG-BMI) and all-cause mortality rate and to determine valuable predictive factors for the survival status of patients with cardiovascular disease (CVD).MethodsConduct a study on CVD patients in the NHANES database from 2007 to 2016. Patients were divided into four groups based on the weighted quartiles of TyG-BMI. Kaplan-Meier curves, Cox regression, and restricted cubic spline (RCS) were used to analyze the correlation between this index and all-cause mortality. Receiver operating characteristic (ROC) curves were used to evaluate its predictive ability, sensitivity, and specificity.ResultsThis study included 1085 patients, and revealed significant differences in survival rates among patients with different TyG-BMI levels. Patients in the higher TyG-BMI group have a lower mortality risk, yet there is no evident non-linear relationship. The ROC curve indicates that this indicator can serve as a predictive value for mortality in CVD patients, demonstrating good sensitivity and specificity.ConclusionThis study found a significant association between TyG-BMI index and all-cause mortality in patients with CVD. TyG-BMI can be used as a predictive indicator of all-cause mortality in CVD patients.https://www.frontiersin.org/articles/10.3389/fendo.2025.1529004/fullNHANESTyG-BMIcardiovascular diseaseTyG indexCVD (cardio vascular disease) |
| spellingShingle | Yiaoran Sun Yiaoran Sun Yuecheng Hu Yuecheng Hu Association of triglyceride-glucose-body mass index with all-cause mortality among individuals with cardiovascular disease: results from NHANES Frontiers in Endocrinology NHANES TyG-BMI cardiovascular disease TyG index CVD (cardio vascular disease) |
| title | Association of triglyceride-glucose-body mass index with all-cause mortality among individuals with cardiovascular disease: results from NHANES |
| title_full | Association of triglyceride-glucose-body mass index with all-cause mortality among individuals with cardiovascular disease: results from NHANES |
| title_fullStr | Association of triglyceride-glucose-body mass index with all-cause mortality among individuals with cardiovascular disease: results from NHANES |
| title_full_unstemmed | Association of triglyceride-glucose-body mass index with all-cause mortality among individuals with cardiovascular disease: results from NHANES |
| title_short | Association of triglyceride-glucose-body mass index with all-cause mortality among individuals with cardiovascular disease: results from NHANES |
| title_sort | association of triglyceride glucose body mass index with all cause mortality among individuals with cardiovascular disease results from nhanes |
| topic | NHANES TyG-BMI cardiovascular disease TyG index CVD (cardio vascular disease) |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2025.1529004/full |
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