Serum Dechlorane Plus (DPs) levels in thyroid disease patients: Influence of gender, age, and metastasis

The study revealed that the serum DPs concentrations in thyroid patients ranged from 2.45 to 141.25 ng/g lw, with the female group showing higher DPs concentrations and a higher fanti value than males. Younger participants exhibited had higher serum DPs concentrations and fanti values compared to ol...

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Bibliographic Details
Main Authors: Ye Wu, Yuhao Fan, Xinyu Lou, Dan Chen, Jun jin, Ying Wang, Ting Yang, Zhiyan Liu
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Ecotoxicology and Environmental Safety
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Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325007468
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Summary:The study revealed that the serum DPs concentrations in thyroid patients ranged from 2.45 to 141.25 ng/g lw, with the female group showing higher DPs concentrations and a higher fanti value than males. Younger participants exhibited had higher serum DPs concentrations and fanti values compared to older age groups, compared to middle-aged and elderly groups, indicating a tendency for anti-DP accumulation. In addition, the fanti value was found to be lower in patients with metastatic thyroid tumor, potentially due to an enhanced capacity to metabolize anti-DP post-metastasis. We also examined the population of patients with varying diameters. Consequently, future studies should further investigate the possible relationship between DPs and thyroid function, with an emphasis on anti-DP.
ISSN:0147-6513