Retrospective study on NIPT or NIPT plus combined with ultrasound in screening fetal chromosomal abnormalities

Abstract This retrospective study analyzed 306 pregnant women, with 182 undergoing genetic testing using NIPT plus and CMA, and 124 undergoing standard NIPT and CMA. The study aimed to compare the clinical performance of NIPT and NIPT plus in prenatal evaluation by using CMA as the gold standard to...

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Bibliographic Details
Main Authors: Meilin Chen, Peisong Chen, Siyang Yu, Lu Ai, Xuegao Yu, Ruizhi Wang, Jinghai Yan, Shaobin Lin
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-97230-w
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