Genetic determinants of pOXA-48 plasmid maintenance and propagation in Escherichia coli

Genetic determinants of pOXA-48 plasmid maintenance and propagation in Escherichia coli

Abstract Conjugative plasmids are the main drivers of antibiotic resistance dissemination contributing to the emergence and extensive spread of multidrug resistance clinical bacterial pathogens. pOXA-48 plasmids, belonging to the IncL group, emerge as the primary vehicle for carbapenem resistance in...

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Main Authors: Yannick Baffert, Nathan Fraikin, Yasmine Makhloufi, Julie Baltenneck, Marie-Eve Val, Annick Dedieu-Berne, Jonathan Degosserie, Bogdan I. Iorga, Pierre Bogaerts, Erwan Gueguen, Christian Lesterlin, Sarah Bigot
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62404-7
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