High-throughput quantitation of human neutrophil recruitment and functional responses in an air-blood barrier array

Dysregulated neutrophil recruitment drives many pulmonary diseases, but most preclinical screening methods are unsuited to evaluate pulmonary neutrophilia, limiting progress toward therapeutics. Namely, high-throughput therapeutic assays typically exclude critical neutrophilic pathophysiology, inclu...

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Main Authors: Hannah Viola, Liang-Hsin Chen, Seongbin Jo, Kendra Washington, Cauviya Selva, Andrea Li, Daniel Feng, Vincent Giacalone, Susan T. Stephenson, Kirsten Cottrill, Ahmad Mohammad, Evelyn Williams, Xianggui Qu, Wilbur Lam, Nga L. Ng, Anne Fitzpatrick, Jocelyn Grunwell, Rabindra Tirouvanziam, Shuichi Takayama
Format: Article
Language:English
Published: AIP Publishing LLC 2025-06-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0220367
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