Liver transcriptomics-metabolomics integration reveals biological pathways associated with fetal programming in beef cattle

Liver transcriptomics-metabolomics integration reveals biological pathways associated with fetal programming in beef cattle

Abstract We investigated the long-term effects of prenatal nutrition on pre-slaughter Nelore bulls using integrative transcriptome and metabolome analyses of liver tissue. Three prenatal nutritional treatments were administered to 126 cows: NP (control, mineral supplementation only), PP (protein-ene...

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Main Authors: Guilherme Henrique Gebim Polizel, Simara Larissa Fanalli, Wellison J. S. Diniz, Aline Silva Mello Cesar, Nara Regina Brandão Cônsolo, Heidge Fukumasu, Angela Cánovas, Arícia Christofaro Fernandes, Barbara Carolina Teixeira Prati, Édison Furlan, Gabriela do Vale Pombo, Miguel Henrique de Almeida Santana
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Maternal nutrition
Metabolites
RNA-seq
Systems biology
WGCNA
Online Access:https://doi.org/10.1038/s41598-024-78965-4
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https://doi.org/10.1038/s41598-024-78965-4

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