A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch

Background. Compliance mismatch is a negative factor and it needs to be considered in arterial bypass grafting. Objective. A computational model was employed to investigate the effects of arterial compliance mismatch on blood flow, wall stress, and deformation. Methods. The unsteady blood flow was a...

Full description

Saved in:
Bibliographic Details
Main Authors: Fan He, Lu Hua, Li-jian Gao
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Applied Bionics and Biomechanics
Online Access:http://dx.doi.org/10.1155/2015/213236
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832556020286619648
author Fan He
Lu Hua
Li-jian Gao
author_facet Fan He
Lu Hua
Li-jian Gao
author_sort Fan He
collection DOAJ
description Background. Compliance mismatch is a negative factor and it needs to be considered in arterial bypass grafting. Objective. A computational model was employed to investigate the effects of arterial compliance mismatch on blood flow, wall stress, and deformation. Methods. The unsteady blood flow was assumed to be laminar, Newtonian, viscous, and incompressible. The vessel wall was assumed to be linear elastic, isotropic, and incompressible. The fluid-wall interaction scheme was constructed using the finite element method. Results. The results show that there are identical wall shear stress waveforms, wall stress, and strain waveforms at different locations. The comparison of the results demonstrates that wall shear stresses and wall strains are higher while wall stresses are lower at the more compliant section. The differences promote the probability of intimal thickening at some locations. Conclusions. The model is effective and gives satisfactory results. It could be extended to all kinds of arteries with complicated geometrical and material factors.
format Article
id doaj-art-cc6577616bbe488f8b97e041cedaf3c0
institution Kabale University
issn 1176-2322
1754-2103
language English
publishDate 2015-01-01
publisher Wiley
record_format Article
series Applied Bionics and Biomechanics
spelling doaj-art-cc6577616bbe488f8b97e041cedaf3c02025-02-03T05:46:37ZengWileyApplied Bionics and Biomechanics1176-23221754-21032015-01-01201510.1155/2015/213236213236A Computational Model for Biomechanical Effects of Arterial Compliance MismatchFan He0Lu Hua1Li-jian Gao2Department of Mechanics, School of Science, Beijing University of Civil Engineering and Architecture, Beijing 100044, ChinaKey Laboratory of Clinical Trial Research in Cardiovascular Drugs, Ministry of Health, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing 100037, ChinaKey Laboratory of Clinical Trial Research in Cardiovascular Drugs, Ministry of Health, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing 100037, ChinaBackground. Compliance mismatch is a negative factor and it needs to be considered in arterial bypass grafting. Objective. A computational model was employed to investigate the effects of arterial compliance mismatch on blood flow, wall stress, and deformation. Methods. The unsteady blood flow was assumed to be laminar, Newtonian, viscous, and incompressible. The vessel wall was assumed to be linear elastic, isotropic, and incompressible. The fluid-wall interaction scheme was constructed using the finite element method. Results. The results show that there are identical wall shear stress waveforms, wall stress, and strain waveforms at different locations. The comparison of the results demonstrates that wall shear stresses and wall strains are higher while wall stresses are lower at the more compliant section. The differences promote the probability of intimal thickening at some locations. Conclusions. The model is effective and gives satisfactory results. It could be extended to all kinds of arteries with complicated geometrical and material factors.http://dx.doi.org/10.1155/2015/213236
spellingShingle Fan He
Lu Hua
Li-jian Gao
A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch
Applied Bionics and Biomechanics
title A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch
title_full A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch
title_fullStr A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch
title_full_unstemmed A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch
title_short A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch
title_sort computational model for biomechanical effects of arterial compliance mismatch
url http://dx.doi.org/10.1155/2015/213236
work_keys_str_mv AT fanhe acomputationalmodelforbiomechanicaleffectsofarterialcompliancemismatch
AT luhua acomputationalmodelforbiomechanicaleffectsofarterialcompliancemismatch
AT lijiangao acomputationalmodelforbiomechanicaleffectsofarterialcompliancemismatch
AT fanhe computationalmodelforbiomechanicaleffectsofarterialcompliancemismatch
AT luhua computationalmodelforbiomechanicaleffectsofarterialcompliancemismatch
AT lijiangao computationalmodelforbiomechanicaleffectsofarterialcompliancemismatch