A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch
Background. Compliance mismatch is a negative factor and it needs to be considered in arterial bypass grafting. Objective. A computational model was employed to investigate the effects of arterial compliance mismatch on blood flow, wall stress, and deformation. Methods. The unsteady blood flow was a...
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Wiley
2015-01-01
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Series: | Applied Bionics and Biomechanics |
Online Access: | http://dx.doi.org/10.1155/2015/213236 |
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author | Fan He Lu Hua Li-jian Gao |
author_facet | Fan He Lu Hua Li-jian Gao |
author_sort | Fan He |
collection | DOAJ |
description | Background. Compliance mismatch is a negative factor and it needs to be considered in arterial bypass grafting. Objective. A computational model was employed to investigate the effects of arterial compliance mismatch on blood flow, wall stress, and deformation. Methods. The unsteady blood flow was assumed to be laminar, Newtonian, viscous, and incompressible. The vessel wall was assumed to be linear elastic, isotropic, and incompressible. The fluid-wall interaction scheme was constructed using the finite element method. Results. The results show that there are identical wall shear stress waveforms, wall stress, and strain waveforms at different locations. The comparison of the results demonstrates that wall shear stresses and wall strains are higher while wall stresses are lower at the more compliant section. The differences promote the probability of intimal thickening at some locations. Conclusions. The model is effective and gives satisfactory results. It could be extended to all kinds of arteries with complicated geometrical and material factors. |
format | Article |
id | doaj-art-cc6577616bbe488f8b97e041cedaf3c0 |
institution | Kabale University |
issn | 1176-2322 1754-2103 |
language | English |
publishDate | 2015-01-01 |
publisher | Wiley |
record_format | Article |
series | Applied Bionics and Biomechanics |
spelling | doaj-art-cc6577616bbe488f8b97e041cedaf3c02025-02-03T05:46:37ZengWileyApplied Bionics and Biomechanics1176-23221754-21032015-01-01201510.1155/2015/213236213236A Computational Model for Biomechanical Effects of Arterial Compliance MismatchFan He0Lu Hua1Li-jian Gao2Department of Mechanics, School of Science, Beijing University of Civil Engineering and Architecture, Beijing 100044, ChinaKey Laboratory of Clinical Trial Research in Cardiovascular Drugs, Ministry of Health, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing 100037, ChinaKey Laboratory of Clinical Trial Research in Cardiovascular Drugs, Ministry of Health, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, and Peking Union Medical College, Beijing 100037, ChinaBackground. Compliance mismatch is a negative factor and it needs to be considered in arterial bypass grafting. Objective. A computational model was employed to investigate the effects of arterial compliance mismatch on blood flow, wall stress, and deformation. Methods. The unsteady blood flow was assumed to be laminar, Newtonian, viscous, and incompressible. The vessel wall was assumed to be linear elastic, isotropic, and incompressible. The fluid-wall interaction scheme was constructed using the finite element method. Results. The results show that there are identical wall shear stress waveforms, wall stress, and strain waveforms at different locations. The comparison of the results demonstrates that wall shear stresses and wall strains are higher while wall stresses are lower at the more compliant section. The differences promote the probability of intimal thickening at some locations. Conclusions. The model is effective and gives satisfactory results. It could be extended to all kinds of arteries with complicated geometrical and material factors.http://dx.doi.org/10.1155/2015/213236 |
spellingShingle | Fan He Lu Hua Li-jian Gao A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch Applied Bionics and Biomechanics |
title | A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch |
title_full | A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch |
title_fullStr | A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch |
title_full_unstemmed | A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch |
title_short | A Computational Model for Biomechanical Effects of Arterial Compliance Mismatch |
title_sort | computational model for biomechanical effects of arterial compliance mismatch |
url | http://dx.doi.org/10.1155/2015/213236 |
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