High concordance of human immunodeficiency virus-1 genotypic drug resistance generated from paired cerebrospinal fluid and plasma in antiretroviral therapy -naive or -experienced patients

High concordance of human immunodeficiency virus-1 genotypic drug resistance generated from paired cerebrospinal fluid and plasma in antiretroviral therapy -naive or -experienced patients

BackgroundThe development of human immunodeficiency virus (HIV) drug resistance significantly impairs patients’ quality of life. However, the HIV-1 drug resistance patterns in the central nervous system (CNS) have been poorly studied.ObjectiveWe aimed to compare HIV-1 genotypes and drug resistance m...

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Bibliographic Details
Main Authors: Xizi Deng, Jiaojiao Li, Ruiying He, Yingfen Wen, Yaqing Lin, Liya Li, Xuemei Ling, Fengyu Hu, Linghua Li, Yun Lan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Microbiology
Subjects:
HIV-1
CSF
plasma
drug resistance
genotype
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1518225/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1518225/full

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