Evolution is in the details: Regulatory differences in modern human and Neanderthal

Transcription factor (TF) proteins play a critical role in the regulation of eukaryote gene expression via sequence-specific binding to genomic locations known as TF binding sites. We studied sites of genomic variation between modern human and Neanderthal promoters. We detected significant differenc...

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Bibliographic Details
Main Authors: Harlan R. Barker, Seppo Parkkila, Martti E.E. Tolvanen
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Computational and Structural Biotechnology Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S2001037025002156
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