Acute Liver Injury with Severe Coagulopathy in Marasmus Caused by a Somatic Delusional Disorder
Marasmus is a severe form of protein-calorie malnutrition characterized by the depletion of fat stores, muscle wasting, and the lack of edema. In developed countries, marasmus is often the result of anorex...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2011/176894 |
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| author | Lance L. Stein Arun B. Jesudian |
| author_facet | Lance L. Stein Arun B. Jesudian |
| author_sort | Lance L. Stein |
| collection | DOAJ |
| description | Marasmus is a severe
form of protein-calorie malnutrition
characterized by the depletion of fat stores,
muscle wasting, and the lack of edema. In
developed countries, marasmus is often the
result of anorexia nervosa. Abnormal
transaminases with liver synthetic dysfunction
have rarely been reported with anorexia nervosa.
To our knowledge, we report the first detailed
case of acute liver injury with severe
coagulopathy (INR>1.5) in a patient with marasmus due to self-induced
calorie restriction caused by a somatic delusional disorder. This
case highlights the severity of liver injury that may occur with
significant weight loss from self-induced calorie restriction and
the rapid normalization of this injury with treatment. It is
important for clinicians to be aware of patterns of acute liver
injury in patients with severe protein-calorie malnutrition,
regardless of the underlying cause. |
| format | Article |
| id | doaj-art-cc235e744092433a860c2e1d1c3b878c |
| institution | Kabale University |
| issn | 2090-6587 2090-6595 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hepatology |
| spelling | doaj-art-cc235e744092433a860c2e1d1c3b878c2025-02-03T01:32:14ZengWileyCase Reports in Hepatology2090-65872090-65952011-01-01201110.1155/2011/176894176894Acute Liver Injury with Severe Coagulopathy in Marasmus Caused by a Somatic Delusional DisorderLance L. Stein0Arun B. Jesudian1Piedmont Transplant Institute, Piedmont Hospital, 1968 Peachtree Road NW, 77 Building, 6th Floor, Atlanta, GA 30309, USADivision of Gastroenterology, New York Presbyterian Hospital, Weill Medical College of Cornell University, 1305 York Avenue, 4th Floor, New York, NY 10021, USAMarasmus is a severe form of protein-calorie malnutrition characterized by the depletion of fat stores, muscle wasting, and the lack of edema. In developed countries, marasmus is often the result of anorexia nervosa. Abnormal transaminases with liver synthetic dysfunction have rarely been reported with anorexia nervosa. To our knowledge, we report the first detailed case of acute liver injury with severe coagulopathy (INR>1.5) in a patient with marasmus due to self-induced calorie restriction caused by a somatic delusional disorder. This case highlights the severity of liver injury that may occur with significant weight loss from self-induced calorie restriction and the rapid normalization of this injury with treatment. It is important for clinicians to be aware of patterns of acute liver injury in patients with severe protein-calorie malnutrition, regardless of the underlying cause.http://dx.doi.org/10.1155/2011/176894 |
| spellingShingle | Lance L. Stein Arun B. Jesudian Acute Liver Injury with Severe Coagulopathy in Marasmus Caused by a Somatic Delusional Disorder Case Reports in Hepatology |
| title | Acute Liver Injury with Severe Coagulopathy in Marasmus Caused by a Somatic Delusional Disorder |
| title_full | Acute Liver Injury with Severe Coagulopathy in Marasmus Caused by a Somatic Delusional Disorder |
| title_fullStr | Acute Liver Injury with Severe Coagulopathy in Marasmus Caused by a Somatic Delusional Disorder |
| title_full_unstemmed | Acute Liver Injury with Severe Coagulopathy in Marasmus Caused by a Somatic Delusional Disorder |
| title_short | Acute Liver Injury with Severe Coagulopathy in Marasmus Caused by a Somatic Delusional Disorder |
| title_sort | acute liver injury with severe coagulopathy in marasmus caused by a somatic delusional disorder |
| url | http://dx.doi.org/10.1155/2011/176894 |
| work_keys_str_mv | AT lancelstein acuteliverinjurywithseverecoagulopathyinmarasmuscausedbyasomaticdelusionaldisorder AT arunbjesudian acuteliverinjurywithseverecoagulopathyinmarasmuscausedbyasomaticdelusionaldisorder |