Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder
Abstract The nucleolus is essential for ribosome biogenesis and is involved in many other cellular functions. We performed a systematic spatiotemporal dissection of the human nucleolar proteome using confocal microscopy. In total, 1,318 nucleolar proteins were identified; 287 were localized to fibri...
Saved in:
| Main Authors: | Lovisa Stenström, Diana Mahdessian, Christian Gnann, Anthony J Cesnik, Wei Ouyang, Manuel D Leonetti, Mathias Uhlén, Sara Cuylen‐Haering, Peter J Thul, Emma Lundberg |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2020-08-01
|
| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/msb.20209469 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Nucleolar origins: challenging perspectives on evolution and function
by: Israel Muñoz-Velasco, et al.
Published: (2025-03-01) -
A Nucleolar Protein, MoRRP8 Is Required for Development and Pathogenicity in the Rice Blast Fungus
by: Minji Kim, et al.
Published: (2023-09-01) -
RNA Pol-II transcripts in nucleolar associated domains of cancer cell nucleoli
by: Soumya Roy Chowdhury, et al.
Published: (2025-12-01) -
Sub-Nucleolar Trafficking of Hendra Virus Matrix Protein Is Regulated by Ubiquitination
by: Tianyue Zhao, et al.
Published: (2025-05-01) -
Expose flexible conformations for intrinsically disordered protein
by: Jiaan Yang, et al.
Published: (2025-12-01)