Caffeic Acid Phenethyl Ester (CAPE) Inhibits Arginase Activity and Growth of <i>Leishmania amazonensis</i> Promastigotes and Intracellular Amastigotes

Caffeic Acid Phenethyl Ester (CAPE) Inhibits Arginase Activity and Growth of <i>Leishmania amazonensis</i> Promastigotes and Intracellular Amastigotes

Caffeic acid phenethyl ester (CAPE) is a polyphenol produced by many plants and is found in red and green propolis. Here, we evaluated the antileishmanial activity of this natural product against <i>Leishmania amazonensis</i>. CAPE exhibited IC<sub>50</sub> values of 8.07 µM...

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Bibliographic Details
Main Authors: Edson Roberto da Silva, André Mesquita, Claudia do Carmo Maquiaveli
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pathogens
Subjects:
antileishamanials
arginase
caffeic acid
polyamines
cutaneous leishmaniasis
Online Access:https://www.mdpi.com/2076-0817/14/4/384
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