Vitrectomy, subretinal Tissue plasminogen activator and Intravitreal Gas for submacular haemorrhage secondary to Exudative Age-Related macular degeneration (TIGER): update to study protocol and addition of a statistical analysis plan and health economic analysis plan for a randomised controlled surgical trial

Vitrectomy, subretinal Tissue plasminogen activator and Intravitreal Gas for submacular haemorrhage secondary to Exudative Age-Related macular degeneration (TIGER): update to study protocol and addition of a statistical analysis plan and health economic analysis plan for a randomised controlled surgical trial

Abstract Background The vitrectomy, subretinal Tissue plasminogen activator and Intravitreal Gas for submacular haemorrhage secondary to Exudative Age-Related macular degeneration (TIGER) trial is a pan-European, two-group, non-commercial, active-control, observer-masked, superiority, randomised con...

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Main Authors: Chan Ning Lee, Riti Desai, Lisa Ramazzotto, Hatem Wafa, Yanzhong Wang, Catey Bunce, Kodchawan Doungsong, Victory Ezeofor, Rhiannon T. Edwards, Noemi Lois, David H. Steel, Tunde Peto, Jost Hillenkamp, Jan C. van Meurs, Barnaby C. Reeves, Timothy L. Jackson
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Trials
Subjects:
Submacular haemorrhage
Vitrectomy
Surgery
Randomised controlled trial
Statistical analysis
Health economic analysis
Online Access:https://doi.org/10.1186/s13063-025-08727-8
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