Examining the Formalin Fixation Method for Maintaining High RNA Quality in Surgical Lung Specimens

Examining the Formalin Fixation Method for Maintaining High RNA Quality in Surgical Lung Specimens

ABSTRACT Background Multiplex genetic testing is recommended when treating nonsmall cell lung cancer. A certain percentage of test failures in RNA assays owing to poor surgical specimen quality have been documented, and fixation failure is a possible cause. At our institution, sheet‐like fixation is...

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Main Authors: Takashi Teishikata, Manabu Itoh, Yusuke Okamoto, Naofumi Miyahara, Chiho Nakashima, Koichiro Takahashi, Masafumi Hiratsuka, Keita Kai, Keiji Kamohara
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Thoracic Cancer
Subjects:
lung cancer
multiplex gene‐panel testing
RNA preservation
Online Access:https://doi.org/10.1111/1759-7714.70005
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https://doi.org/10.1111/1759-7714.70005

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