Diminished DEFA6 Expression in Paneth Cells Is Associated with Necrotizing Enterocolitis

Diminished DEFA6 Expression in Paneth Cells Is Associated with Necrotizing Enterocolitis

Background. Necrotizing enterocolitis (NEC) is the most common gastrointestinal disorder in premature infants with a high morbidity and mortality. Paneth cell dysfunction has been suggested to be involved in the pathogenesis of NEC. Defensin alpha-6 (DEFA6) is a specific marker for Paneth cells acti...

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Bibliographic Details
Main Authors: Laszlo Markasz, Alkwin Wanders, Laszlo Szekely, Helene Engstrand Lilja
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2018/7345426
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