Structural characterization and dynamics of AdhE ultrastructures from Clostridium thermocellum show a containment strategy for toxic intermediates

Structural characterization and dynamics of AdhE ultrastructures from Clostridium thermocellum show a containment strategy for toxic intermediates

Clostridium thermocellum, a cellulolytic thermophilic anaerobe, is considered by many to be a prime candidate for the realization of consolidated bioprocessing (CBP) and is known as an industry standard for biofuel production. C. thermocellum is among the best biomass degraders identified to date in...

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Bibliographic Details
Main Authors: Samantha J Ziegler, Brandon C Knott, Josephine N Gruber, Neal N Hengge, Qi Xu, Daniel G Olson, Eduardo E Romero, Lydia-Marie Joubert, Yannick J Bomble
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-06-01
Series:eLife
Subjects:
C. thermocellum
aldehyde-alcohol dehydrogenase
substrate channeling
cofactors
cryo-EM
thermophiles
Online Access:https://elifesciences.org/articles/96966
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