Multimodal DTI-ALPS and hippocampal microstructural signatures unveil stage-specific pathways in Alzheimer’s disease progression

ObjectiveDevelop a multimodal biomarker framework integrating DTI-ALPS (Diffusion Tensor Imaging along the Perivascular Space), hippocampal diffusivity, and CSF profiles for staging Alzheimer’s disease (AD) progression across the HC → MCI → AD continuum.MethodsCross-sectional analysis of 60 age-matc...

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Bibliographic Details
Main Authors: Peng Yu, Lu Shen, Lijun Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Aging Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1609793/full
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