Spontaneous Cell Detachment from Temperature Gradients: Getting the Method Ready for Antimicrobial Drug Testing at Cell Culture Level

Spontaneous Cell Detachment from Temperature Gradients: Getting the Method Ready for Antimicrobial Drug Testing at Cell Culture Level

Spontaneous cell detachment describes an effect in which eukaryotic cells first sediment onto a heated chip and then detach from it spontaneously and collectively after a sharply defined dwell time <i>t<sub>d</sub></i>. This behavior is triggered by the temperature gradient b...

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Bibliographic Details
Main Authors: Csongor Tibor Urbán, Soroush Bakhshi Sichani, Gabriela Ueda Modaffore, Christ Glorieux, Jonas Gruber, Derick Yongabi, Minne Paul Lettinga, Patrick Wagner
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Sensors
Subjects:
cell-based biosensors
<i>S. cerevisiae</i>
heat-transfer method HTM
temperature gradients
spontaneous cell detachment
microfluidic aspect ratio
Online Access:https://www.mdpi.com/1424-8220/25/9/2902
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