High-rate mechano-stimulation alters proliferation- and maturation-related signaling of oligodendrocyte precursor cells in a 3D hydrogel

High-rate mechano-stimulation alters proliferation- and maturation-related signaling of oligodendrocyte precursor cells in a 3D hydrogel

Traumatic brain injury (TBI) leads to neuroinflammation and is associated with chronic neurodegeneration. Many TBI studies aim to understand further the mechanism by which cells in the brain respond to the mechanical forces associated with TBI. In particular, mild TBI is the most common level of inj...

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Bibliographic Details
Main Authors: Ryosuke Yokosawa, Rachel A. Mazur, Kelsey A. Wilson, Jacob H. Lee, Noah W. Showalter, Kyle J. Lampe, Pamela J. VandeVord
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Mechanobiology in Medicine
Subjects:
Traumatic brain injury
Oligodendrocyte precursor cell
Hydrogel
Cell proliferation
Cell maturation
Mechanobiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2949907025000142
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http://www.sciencedirect.com/science/article/pii/S2949907025000142

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