De-risking vaccine development: lessons, challenges, and prospects

Abstract Vaccine development is long and costly. Technical, clinical, regulatory, and manufacturing risks throughout the development cycle hampered manufacturers’ efforts towards more challenging and financially less rewarding targets, with profound implications for public health. Early de-risking s...

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Bibliographic Details
Main Authors: Vega Masignani, Ricardo Palacios, Marie-Thérèse Martin, Fabian Tibaldi, V. Kumaran Vadivelu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-025-01211-z
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