Defaulting from antiretroviral therapy and associated factors among HIV/AIDS patients in public hospitals of Eastern Zone, Tigray, Ethiopia, 2020: a cross-sectional study
Background Globally, over 76 million people have been infected with human immunodeficiency virus (HIV), and the infection has contributed to more than 35 million deaths since its emergence. Studies revealed that in developing countries, defaulting patients were outnumbering patients who were known t...
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Termedia Publishing House
2024-11-01
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| Series: | HIV & AIDS Review. International Journal of HIV-Related Problems |
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| Online Access: | https://hivaids.termedia.pl/Defaulting-from-antiretroviral-therapy-and-associated-factors-among-HIV-AIDS-patients,172170,0,2.html |
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| _version_ | 1832584820033585152 |
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| author | Tsegu Hailu Gebru Haftea Hagos Mekonen |
| author_facet | Tsegu Hailu Gebru Haftea Hagos Mekonen |
| author_sort | Tsegu Hailu Gebru |
| collection | DOAJ |
| description | Background
Globally, over 76 million people have been infected with human immunodeficiency virus (HIV), and the infection has contributed to more than 35 million deaths since its emergence. Studies revealed that in developing countries, defaulting patients were outnumbering patients who were known to have died. The burden of defaulting and associated factors among adults receiving antiretroviral therapy (ART) is lacking in this particular study area. Therefore, this study aimed to assess the prevalence of defaulting and associated factors among adult HIV/AIDS patients receiving antiretroviral therapy in Eastern Zone, Tigray, Ethiopia.
Material and methods
A structured questionnaire was employed to collect data from 501 study participants through an interview. The required sample size was determined with a single population proportion formula. Participants were selected using a systematic random sampling method. Data were entered and analyzed with Statistical Package for Social Science (SPSS) version 22. Multivariable logistic regression analysis was used to obtain factors, with p-value < 0.05.
Results
The mean age of participants was 40.97 (± 9.35) years. The prevalence of defaulting was 25% (95% CI: 21.2-29.1%). Side effects of ART, mental instability, poor adherence to ART, and high pill burden were independently associated with defaulting from ART.
Conclusions
The results of the study indicated that defaulting was high. Furthermore, participants with high pill burden, drug toxicity, mental instability, and poor ART adherence were more likely to default from the treatment. Healthcare providers should advise HIV patients to improve adherence to treatment, and highlight its importance as a priority issue. |
| format | Article |
| id | doaj-art-cb65a1bdff4b4d7d9e09705de1c5ee54 |
| institution | Kabale University |
| issn | 1730-1270 1732-2707 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | HIV & AIDS Review. International Journal of HIV-Related Problems |
| spelling | doaj-art-cb65a1bdff4b4d7d9e09705de1c5ee542025-01-27T11:06:39ZengTermedia Publishing HouseHIV & AIDS Review. International Journal of HIV-Related Problems1730-12701732-27072024-11-0123431432210.5114/hivar/172170172170Defaulting from antiretroviral therapy and associated factors among HIV/AIDS patients in public hospitals of Eastern Zone, Tigray, Ethiopia, 2020: a cross-sectional studyTsegu Hailu Gebru0Haftea Hagos Mekonen1Adigrat University, Adigrat, EthiopiaAdigrat University, Adigrat, EthiopiaBackground Globally, over 76 million people have been infected with human immunodeficiency virus (HIV), and the infection has contributed to more than 35 million deaths since its emergence. Studies revealed that in developing countries, defaulting patients were outnumbering patients who were known to have died. The burden of defaulting and associated factors among adults receiving antiretroviral therapy (ART) is lacking in this particular study area. Therefore, this study aimed to assess the prevalence of defaulting and associated factors among adult HIV/AIDS patients receiving antiretroviral therapy in Eastern Zone, Tigray, Ethiopia. Material and methods A structured questionnaire was employed to collect data from 501 study participants through an interview. The required sample size was determined with a single population proportion formula. Participants were selected using a systematic random sampling method. Data were entered and analyzed with Statistical Package for Social Science (SPSS) version 22. Multivariable logistic regression analysis was used to obtain factors, with p-value < 0.05. Results The mean age of participants was 40.97 (± 9.35) years. The prevalence of defaulting was 25% (95% CI: 21.2-29.1%). Side effects of ART, mental instability, poor adherence to ART, and high pill burden were independently associated with defaulting from ART. Conclusions The results of the study indicated that defaulting was high. Furthermore, participants with high pill burden, drug toxicity, mental instability, and poor ART adherence were more likely to default from the treatment. Healthcare providers should advise HIV patients to improve adherence to treatment, and highlight its importance as a priority issue.https://hivaids.termedia.pl/Defaulting-from-antiretroviral-therapy-and-associated-factors-among-HIV-AIDS-patients,172170,0,2.htmlethiopiahiv/aidsantiretroviral therapydefaultertigray |
| spellingShingle | Tsegu Hailu Gebru Haftea Hagos Mekonen Defaulting from antiretroviral therapy and associated factors among HIV/AIDS patients in public hospitals of Eastern Zone, Tigray, Ethiopia, 2020: a cross-sectional study HIV & AIDS Review. International Journal of HIV-Related Problems ethiopia hiv/aids antiretroviral therapy defaulter tigray |
| title | Defaulting from antiretroviral therapy and associated factors among HIV/AIDS patients in public hospitals of Eastern Zone, Tigray, Ethiopia, 2020: a cross-sectional study |
| title_full | Defaulting from antiretroviral therapy and associated factors among HIV/AIDS patients in public hospitals of Eastern Zone, Tigray, Ethiopia, 2020: a cross-sectional study |
| title_fullStr | Defaulting from antiretroviral therapy and associated factors among HIV/AIDS patients in public hospitals of Eastern Zone, Tigray, Ethiopia, 2020: a cross-sectional study |
| title_full_unstemmed | Defaulting from antiretroviral therapy and associated factors among HIV/AIDS patients in public hospitals of Eastern Zone, Tigray, Ethiopia, 2020: a cross-sectional study |
| title_short | Defaulting from antiretroviral therapy and associated factors among HIV/AIDS patients in public hospitals of Eastern Zone, Tigray, Ethiopia, 2020: a cross-sectional study |
| title_sort | defaulting from antiretroviral therapy and associated factors among hiv aids patients in public hospitals of eastern zone tigray ethiopia 2020 a cross sectional study |
| topic | ethiopia hiv/aids antiretroviral therapy defaulter tigray |
| url | https://hivaids.termedia.pl/Defaulting-from-antiretroviral-therapy-and-associated-factors-among-HIV-AIDS-patients,172170,0,2.html |
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