Dimethyl fumarate effects on paraquat-induced hepatotoxicity in mice via anti-oxidative, anti-inflammatory, and anti-apoptotic activities

Dimethyl fumarate effects on paraquat-induced hepatotoxicity in mice via anti-oxidative, anti-inflammatory, and anti-apoptotic activities

Abstract Paraquat (PQ) toxicity is a common problem in the world, associated with oxidative stress, inflammation, and apoptosis. Therefore, the use of agents that reduce these disorders can be effective in the treatment of PQ toxicity. The protective effects of dimethyl fumarate (DMF) on liver disor...

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Bibliographic Details
Main Authors: Maryam Kavianinia, Hadi Kalantar, Maryam Salehcheh, Layasadat Khorsandi, Saeedeh Shariati, Shokooh Mohtadi, Mohammad Javad Khodayar
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Paraquat
Oxidative stress
Inflammation
Apoptosis
Dimethyl fumarate
Hepatotoxicity
Online Access:https://doi.org/10.1038/s41598-025-88461-y
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https://doi.org/10.1038/s41598-025-88461-y

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