Intensive versus less-intensive antileukemic therapy in older adults with acute myeloid leukemia: A systematic review.

Intensive versus less-intensive antileukemic therapy in older adults with acute myeloid leukemia: A systematic review.

To compare the effectiveness and safety of intensive antileukemic therapy to less-intensive therapy in older adults with acute myeloid leukemia (AML) and intermediate or adverse cytogenetics, we searched the literature in Medline, Embase, and CENTRAL to identify relevant studies through July 2020. W...

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Main Authors: Yaping Chang, Gordon H Guyatt, Trevor Teich, Jamie L Dawdy, Shaneela Shahid, Jessica K Altman, Richard M Stone, Mikkael A Sekeres, Sudipto Mukherjee, Thomas W LeBlanc, Gregory A Abel, Christopher S Hourigan, Mark R Litzow, Laura C Michaelis, Shabbir M H Alibhai, Pinkal Desai, Rena Buckstein, Janet MacEachern, Romina Brignardello-Petersen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0249087&type=printable
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