Promoter engineering with programmable upstream activating sequences in Aspergillus Niger cell factory

Promoter engineering with programmable upstream activating sequences in Aspergillus Niger cell factory

Abstract Background Aspergillus niger is an important industrial filamentous fungus used to produce organic acids and enzymes. A wide dynamic range of promoters, particularly strong promoters, are required for fine-tuning the regulation of gene expression to balance metabolic flux and achieve the hi...

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Bibliographic Details
Main Authors: Xiaomei Zheng, Yuting Guo, Meiling Chen, Yudan Lu, Yimou Du, Yu Lei, Ping Zheng, Jibin Sun
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Microbial Cell Factories
Subjects:
Aspergillus Niger
Synthetic promoter
Upstream activation sequence
Fluorescence protein
Citric acid production
Online Access:https://doi.org/10.1186/s12934-025-02642-y
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https://doi.org/10.1186/s12934-025-02642-y

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