Japanese Phase 1 Study for Global Development of Anti‐TL1A Antibody PF‐06480605: A Randomized, Placebo‐Controlled, Single‐Ascending Dose Study

ABSTRACT PF‐06480605, a fully human IgG1 monoclonal antibody targeting tumor necrosis factor α‐like ligand 1A (TL1A), has demonstrated acceptable safety and the potential as an effective treatment for inflammatory bowel disease in phase 1/2a studies. To facilitate future clinical development in Japa...

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Bibliographic Details
Main Authors: Kei Fukuhara, Srividya Neelakantan, Kenichi Furihata, Hirotoshi Yuasa, Nanzhi Shi, Yuichi Yamamoto, Kenneth E. Hung
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Clinical and Translational Science
Subjects:
Online Access:https://doi.org/10.1111/cts.70187
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