Kinetic Assessment and Therapeutic Modulation of Metabolic and Inflammatory Profiles in Mice on a High-Fat and Cholesterol Diet

Kinetic Assessment and Therapeutic Modulation of Metabolic and Inflammatory Profiles in Mice on a High-Fat and Cholesterol Diet

The kinetics of metabolic and inflammatory parameters associated with obesity were evaluated in a murine diet-induced obesity (DIO) model using a diet high in fat and cholesterol. Cellular infiltration and mediator production were assessed and shown to be therapeutically modulated by the PPARgamma a...

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Main Authors: Laura W. Engstrom, Loretta Bober, Shu-Cheng Chen, Jay S. Fine, Ying Li, Michaela C. Stanton, David Kinsley, Long Cui, James V. Jackson, Alberto Rojas-Triana, Daniel Lundell, Maureen Laverty, Eric L. Gustafson, Chung-Her Jenh, Timothy J. Kowalski, Denise J. Manfra
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2010/970164
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http://dx.doi.org/10.1155/2010/970164

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