Ion channel traffic jams: the significance of trafficking deficiency in long QT syndrome

Abstract A well-balanced ion channel trafficking machinery is paramount for the normal electromechanical function of the heart. Ion channel variants and many drugs can alter the cardiac action potential and lead to arrhythmias by interfering with mechanisms like ion channel synthesis, trafficking, g...

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Bibliographic Details
Main Authors: Gema Mondéjar-Parreño, Ana I. Moreno-Manuel, Juan Manuel Ruiz-Robles, José Jalife
Format: Article
Language:English
Published: Nature Publishing Group 2025-01-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-024-00738-0
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