Modulation of DAPK1 expression by its alternative splice variant DAPK1-215 in cancer

Modulation of DAPK1 expression by its alternative splice variant DAPK1-215 in cancer

Abstract Background Death-Associated Protein Kinase 1 (DAPK1) family members are calcium/calmodulin-regulated serine/threonine kinases implicated in cell death, normal development, and human diseases. However, the regulation of DAPK1 expression in cancer remains unclear. Methods We examined the expr...

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Main Authors: QingShui Wang, ShuYun Weng, WenTing Zhong, YouYu Lin, Yan Yu, YiMin Huang, LiLin Ge, XiuLi Zhang, FangQin Xue, Yehuda G. Assaraf, Yao Lin
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Translational Medicine
Subjects:
DAPK1
DAPK1-215
DDX3X
MRNA stability
Cancer progression
Online Access:https://doi.org/10.1186/s12967-025-06127-9
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https://doi.org/10.1186/s12967-025-06127-9

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