Real-time monitoring by interferometric light microscopy of phage suspensions for personalised phage therapy

Real-time monitoring by interferometric light microscopy of phage suspensions for personalised phage therapy

Abstract Phage therapy uses viruses (phages) against antibiotic resistance. Tailoring treatments to specific patient strains requires stocks of various highly concentrated purified phages. It, therefore, faces challenges: titration duration and specificity to a phage/bacteria couple; purification af...

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Bibliographic Details
Main Authors: Benjamine Lapras, Camille Merienne, Emma Eynaud, Léa Usseglio, Chloé Marchand, Mathieu Médina, Camille Kolenda, Thomas Briot, Frédéric Laurent, Fabrice Pirot, PHAGEinLYON
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Bacteriophages
Therapeutic phage suspension
Virus quantification
Fast purification monitoring
Viral stability
Aggregation
Online Access:https://doi.org/10.1038/s41598-024-79478-w
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https://doi.org/10.1038/s41598-024-79478-w

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