Role of Toll-Like Receptors and Their Downstream Molecules in the Development of Nonalcoholic Fatty Liver Disease

Activation of innate immunity is associated with the development of liver disease, including non-alcoholic fatty liver disease (NAFLD). In the innate immune system, Toll-like receptors (TLRs) are sensors that recognize bacterial and viral components such as lipopolysaccharide, bacterial DNA, and pep...

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Bibliographic Details
Main Authors: Kouichi Miura, Ekihiro Seki, Hirohide Ohnishi, David A. Brenner
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2010/362847
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