Aerosol immunization with influenza matrix, nucleoprotein, or both prevents lung disease in pig

Abstract Current influenza vaccines are strain-specific and require frequent updates to combat new strains, making a broadly protective influenza vaccine (BPIV) highly desirable. A promising strategy is to induce T-cell responses against internal proteins conserved across influenza strains. In this...

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Main Authors: Eleni Vatzia, Basudev Paudyal, Barbara Dema, Brigid Veronica Carr, Ehsan Sedaghat-Rostami, Simon Gubbins, Bhawna Sharma, Elliot Moorhouse, Susan Morris, Marta Ulaszewska, Ronan MacLoughlin, Francisco J. Salguero, Sarah C. Gilbert, Elma Tchilian
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-024-00989-8
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