Microstructural and microvascular features of white matter hyperintensities and their association with small vessel disease markers

Microstructural and microvascular features of white matter hyperintensities and their association with small vessel disease markers

Abstract White matter hyperintensities (WMH) are the most prominent imaging feature of small vessel disease (SVD). WMH and other imaging features of SVD are likely the result of ongoing insults associated with cognitive decline and cerebrovascular events. Emerging evidence suggests degradation of th...

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Bibliographic Details
Main Authors: Lily L. Wang, Brady J. Williamson, Bin Zhang, Aakanksha Sriwastawa, Yasmin N. Aziz, Eleni Antzoulatos, Cody B. Stephens, Achala Vagal, Pooja Khatri, Mark W. DiFrancesco
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Small Vessel Disease
Arterial spin labeling
Diffusion-weighted imaging
Blood–brain-barrier
Brain microvasculature
White matter hyperintensities
Online Access:https://doi.org/10.1038/s41598-025-03885-w
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https://doi.org/10.1038/s41598-025-03885-w

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