A Sustainable Approach to Glucose Biosensors: Utilizing Coconut Shell Activated Carbon and NiCaFe₂O₄ Nanoparticles

Diabetes-related mortality can be significantly reduced through early detection of blood glucose levels. This study presents a sustainable approach to glucose biosensors by utilizing coconut shell activated carbon as the working electrode material in a carbon paste electrode for electrochemical gluc...

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Main Authors: Fatoni Amin, Hutama David, Hermawan Dadan, Samanman Saluma, Dwi Anggraeni Mekar
Format: Article
Language:English
Published: EDP Sciences 2025-01-01
Series:E3S Web of Conferences
Online Access:https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/09/e3sconf_icma-sure2024_02002.pdf
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Summary:Diabetes-related mortality can be significantly reduced through early detection of blood glucose levels. This study presents a sustainable approach to glucose biosensors by utilizing coconut shell activated carbon as the working electrode material in a carbon paste electrode for electrochemical glucose detection via cyclic voltammetry. The performance of the electrode was further enhanced with NiCaFe₂ O₄ nanoparticles to improve electron transfer and redox potential. The optimized electrode consisted of a 2:1 ratio of activated carbon to paraffin, incorporating 16% NiCaFe₂ O₄ nanoparticles. Detection of hydrogen peroxide using this modified electrode exhibited an oxidation peak at 0.16 V and a reduction peak at -0.35 V. Optimal glucose detection conditions were achieved in 100 mM phosphate buffer at pH 7.5. Glucose oxidase was immobilized on the modified electrode, showing a linear response for glucose detection at the oxidation peak of 0.66 V. This sustainable biosensor demonstrated high sensitivity and potential for low- cost, eco-friendly glucose monitoring applications.
ISSN:2267-1242