Development of a set of bacterial engineered glycoconjugates as novel serogroup-specific antigens for the serodiagnosis of Escherichia coli O26, O111, O103 and O45 infections associated to hemolytic uremic syndrome

Development of a set of bacterial engineered glycoconjugates as novel serogroup-specific antigens for the serodiagnosis of Escherichia coli O26, O111, O103 and O45 infections associated to hemolytic uremic syndrome

Abstract Hemolytic uremic syndrome associated to Shiga toxin-producing Escherichia coli infection (STEC-HUS) is a life-threatening condition characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney failure. Among STEC, E. coli O157:H7 is the dominant serotype related wi...

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Main Authors: Ana J. Caillava, Luciano J. Melli, Malena Landoni, Stella Maris Landivar, Isabel Chinen, Alicia S. Couto, Marta Rivas, Juan E. Ugalde, Diego J. Comerci, Andrés E. Ciocchini
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Microbial Cell Factories
Online Access:https://doi.org/10.1186/s12934-025-02694-0
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