Multidisciplinary Collaboration and Novel Technological Advances in Hadron Therapy

The battle against cancer remains a top priority for society, with an urgent need to develop therapies capable of targeting challenging tumours while preserving patient's quality of life. Hadron Therapy (HT), which employs accelerated beams of protons, carbon ions, and other charged particles,...

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Main Authors: Manjit Dosanjh PhD, Alberto Degiovanni PhD, Maria Monica Necchi PhD, Elena Benedetto PhD
Format: Article
Language:English
Published: SAGE Publishing 2025-02-01
Series:Technology in Cancer Research & Treatment
Online Access:https://doi.org/10.1177/15330338241311859
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author Manjit Dosanjh PhD
Alberto Degiovanni PhD
Maria Monica Necchi PhD
Elena Benedetto PhD
author_facet Manjit Dosanjh PhD
Alberto Degiovanni PhD
Maria Monica Necchi PhD
Elena Benedetto PhD
author_sort Manjit Dosanjh PhD
collection DOAJ
description The battle against cancer remains a top priority for society, with an urgent need to develop therapies capable of targeting challenging tumours while preserving patient's quality of life. Hadron Therapy (HT), which employs accelerated beams of protons, carbon ions, and other charged particles, represents a significant frontier in cancer treatment. This modality offers superior precision and efficacy compared to conventional methods, delivering therapeutic the dose directly to tumours while sparing healthy tissue. Even though 350,000 patients have already been treated worldwide with protons and 50,000 with carbon ions, HT is still a relatively young field and more research as well as novel, cost-effective and compact accelerator technologies are needed to make this treatment more readily available globally. Interestingly the very first patient was irradiated with protons in September 1954, the same month and year CERN was founded. Both of these endeavours are embedded in cutting edge technologies and multidisciplinary collaboration. HT is finally gaining ground and, even after 70 years, the particle therapy field continues innovating and improving for the benefits of patients globally. Developing technologies that are both affordable and easy to use is key and would allow access to more patients. Advances in accelerator-driven Boron Neutron Capture Therapy (BNCT), image-guided hadron beams delivery, clinical trials and immunotherapy, together with the recent interest and advances in FLASH therapy, which is currently an experimental treatment modality that involves ultrahigh-dose rate delivery, are just a few examples of innovation that may eventually help to provide access to a larger number of patients.
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institution Kabale University
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publishDate 2025-02-01
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series Technology in Cancer Research & Treatment
spelling doaj-art-c9b08d2a0e5e4df2af00f8bfebb163842025-02-03T07:03:52ZengSAGE PublishingTechnology in Cancer Research & Treatment1533-03382025-02-012410.1177/15330338241311859Multidisciplinary Collaboration and Novel Technological Advances in Hadron TherapyManjit Dosanjh PhD0Alberto Degiovanni PhD1 Maria Monica Necchi PhD2Elena Benedetto PhD3 CERN, Geneva, Switzerland , Geneva, Switzerland , Pavia, Lombardia, Italy South East Europe International Institute for Sustainable Technology (SEEIIST) Association, Geneva, SwitzerlandThe battle against cancer remains a top priority for society, with an urgent need to develop therapies capable of targeting challenging tumours while preserving patient's quality of life. Hadron Therapy (HT), which employs accelerated beams of protons, carbon ions, and other charged particles, represents a significant frontier in cancer treatment. This modality offers superior precision and efficacy compared to conventional methods, delivering therapeutic the dose directly to tumours while sparing healthy tissue. Even though 350,000 patients have already been treated worldwide with protons and 50,000 with carbon ions, HT is still a relatively young field and more research as well as novel, cost-effective and compact accelerator technologies are needed to make this treatment more readily available globally. Interestingly the very first patient was irradiated with protons in September 1954, the same month and year CERN was founded. Both of these endeavours are embedded in cutting edge technologies and multidisciplinary collaboration. HT is finally gaining ground and, even after 70 years, the particle therapy field continues innovating and improving for the benefits of patients globally. Developing technologies that are both affordable and easy to use is key and would allow access to more patients. Advances in accelerator-driven Boron Neutron Capture Therapy (BNCT), image-guided hadron beams delivery, clinical trials and immunotherapy, together with the recent interest and advances in FLASH therapy, which is currently an experimental treatment modality that involves ultrahigh-dose rate delivery, are just a few examples of innovation that may eventually help to provide access to a larger number of patients.https://doi.org/10.1177/15330338241311859
spellingShingle Manjit Dosanjh PhD
Alberto Degiovanni PhD
Maria Monica Necchi PhD
Elena Benedetto PhD
Multidisciplinary Collaboration and Novel Technological Advances in Hadron Therapy
Technology in Cancer Research & Treatment
title Multidisciplinary Collaboration and Novel Technological Advances in Hadron Therapy
title_full Multidisciplinary Collaboration and Novel Technological Advances in Hadron Therapy
title_fullStr Multidisciplinary Collaboration and Novel Technological Advances in Hadron Therapy
title_full_unstemmed Multidisciplinary Collaboration and Novel Technological Advances in Hadron Therapy
title_short Multidisciplinary Collaboration and Novel Technological Advances in Hadron Therapy
title_sort multidisciplinary collaboration and novel technological advances in hadron therapy
url https://doi.org/10.1177/15330338241311859
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