Comparison of healing time and the histopathology of bone formation following tooth extraction using freeze-dried bone allograft:A randomized controlled clinical trial
Background. A decrease in the width and height of the alveolar ridge is inevitable following tooth extraction. This study aimed to histologically evaluate the amount of newly formed bone after using a freeze-dried bone allograft (FDBA) at two different intervals in the tooth socket grafting. Method...
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Tabriz University of Medical Sciences
2022-12-01
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| Series: | Journal of Advanced Periodontology and Implant Dentistry |
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| Online Access: | https://japid.tbzmed.ac.ir/PDF/japid-14-69.pdf |
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| author | Omid Moghaddas Nima Naddafpour Sareh Farhadi Peyman Nikookar Sephora Khandan |
| author_facet | Omid Moghaddas Nima Naddafpour Sareh Farhadi Peyman Nikookar Sephora Khandan |
| author_sort | Omid Moghaddas |
| collection | DOAJ |
| description | Background. A decrease in the width and height of the alveolar ridge is inevitable following tooth extraction. This study aimed to histologically evaluate the amount of newly formed bone after using a freeze-dried bone allograft (FDBA) at two different intervals in the tooth socket grafting. Methods. Forty patients were selected, who required a single-rooted tooth extraction and were candidates for implant placement, with no indication for an immediate implant. Extraction sockets were preserved using a cortical FDBA allograft in two regeneration interval groups: 3 months (group A) and 4 months (group B). At the time of implant placement, a bone sample was collected from each grafted socket. Histomorphometric analyses were performed to determine the percentage of newly formed bone and the residual graft material. Changes in histological indices, i.e., inflammation rate, percentage of ossification, and the amount of remaining biomaterial, were evaluated. Results. There were no significant differences in the amount of newly formed bone and residual graft material between the two groups. In general, the average of new bone formation and remaining graft particles in groups A and B was: %33.89 and %12.59 vs. %39.83 and %14.07, respectively. Conclusion. Bone parameters in group A were better compared to group B. However, due to the lack of significant differences in the results, it is suggested that implant placement in grafted sockets with mineralized allografts be expedited. |
| format | Article |
| id | doaj-art-c91b639d622b4b0a9a04a8b3c848cfe8 |
| institution | OA Journals |
| issn | 2645-5390 |
| language | English |
| publishDate | 2022-12-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Advanced Periodontology and Implant Dentistry |
| spelling | doaj-art-c91b639d622b4b0a9a04a8b3c848cfe82025-08-20T02:22:06ZengTabriz University of Medical SciencesJournal of Advanced Periodontology and Implant Dentistry2645-53902022-12-01142697510.34172/japid.2022.020japid-1217Comparison of healing time and the histopathology of bone formation following tooth extraction using freeze-dried bone allograft:A randomized controlled clinical trialOmid Moghaddas0Nima Naddafpour1Sareh Farhadi2Peyman Nikookar3Sephora Khandan4Department of Periodontology, Faculty of Dentistry, Tehran Islamic Azad Medical Sciences University, Tehran, IranDepartment of Periodontology, Faculty of Dentistry, Tehran Islamic Azad Medical Sciences University, Tehran, IranDepartment of Oral and Maxillofacial Pathology, Faculty of Dentistry, Tehran Islamic Azad Medical Sciences University, Tehran, IranGeneral Practitioner, Private Practice, Tehran, IranDental Branch, Tehran Medical Science, Islamic Azad University, Tehran, IranBackground. A decrease in the width and height of the alveolar ridge is inevitable following tooth extraction. This study aimed to histologically evaluate the amount of newly formed bone after using a freeze-dried bone allograft (FDBA) at two different intervals in the tooth socket grafting. Methods. Forty patients were selected, who required a single-rooted tooth extraction and were candidates for implant placement, with no indication for an immediate implant. Extraction sockets were preserved using a cortical FDBA allograft in two regeneration interval groups: 3 months (group A) and 4 months (group B). At the time of implant placement, a bone sample was collected from each grafted socket. Histomorphometric analyses were performed to determine the percentage of newly formed bone and the residual graft material. Changes in histological indices, i.e., inflammation rate, percentage of ossification, and the amount of remaining biomaterial, were evaluated. Results. There were no significant differences in the amount of newly formed bone and residual graft material between the two groups. In general, the average of new bone formation and remaining graft particles in groups A and B was: %33.89 and %12.59 vs. %39.83 and %14.07, respectively. Conclusion. Bone parameters in group A were better compared to group B. However, due to the lack of significant differences in the results, it is suggested that implant placement in grafted sockets with mineralized allografts be expedited.https://japid.tbzmed.ac.ir/PDF/japid-14-69.pdfallograftsalveolar ridge augmentationdental implantbone resorptionbone grafttooth extraction |
| spellingShingle | Omid Moghaddas Nima Naddafpour Sareh Farhadi Peyman Nikookar Sephora Khandan Comparison of healing time and the histopathology of bone formation following tooth extraction using freeze-dried bone allograft:A randomized controlled clinical trial Journal of Advanced Periodontology and Implant Dentistry allografts alveolar ridge augmentation dental implant bone resorption bone graft tooth extraction |
| title | Comparison of healing time and the histopathology of bone formation following tooth extraction using freeze-dried bone allograft:A randomized controlled clinical trial |
| title_full | Comparison of healing time and the histopathology of bone formation following tooth extraction using freeze-dried bone allograft:A randomized controlled clinical trial |
| title_fullStr | Comparison of healing time and the histopathology of bone formation following tooth extraction using freeze-dried bone allograft:A randomized controlled clinical trial |
| title_full_unstemmed | Comparison of healing time and the histopathology of bone formation following tooth extraction using freeze-dried bone allograft:A randomized controlled clinical trial |
| title_short | Comparison of healing time and the histopathology of bone formation following tooth extraction using freeze-dried bone allograft:A randomized controlled clinical trial |
| title_sort | comparison of healing time and the histopathology of bone formation following tooth extraction using freeze dried bone allograft a randomized controlled clinical trial |
| topic | allografts alveolar ridge augmentation dental implant bone resorption bone graft tooth extraction |
| url | https://japid.tbzmed.ac.ir/PDF/japid-14-69.pdf |
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