Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons

Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons

Sensory dorsal root ganglion (DRG) neurons have a unique pseudo-unipolar morphology in which a stem axon bifurcates into a peripheral and a central axon, with different regenerative abilities. Whereas peripheral DRG axons regenerate, central axons are unable to regrow. Central axon regeneration can...

Full description

Saved in:
Bibliographic Details
Main Authors: Ana Catarina Costa, Blanca R Murillo, Rita Bessa, Ricardo Ribeiro, Tiago Ferreira da Silva, Patrícia Porfírio-Rodrigues, Gabriel G Martins, Pedro Brites, Matthias Kneussel, Thomas Misgeld, Monika S Brill, Monica M Sousa
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-02-01
Series:eLife
Subjects:
axon growth
axon regeneration
cargo sorting
conditioning lesion
dorsal root ganglion
microtubules
Online Access:https://elifesciences.org/articles/104069
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://elifesciences.org/articles/104069

Similar Items