Polymorphisms in SAA alter intrarenal amyloid distribution of AA amyloidosis in cats

Polymorphisms in SAA alter intrarenal amyloid distribution of AA amyloidosis in cats

Abstract The kidneys are one of the primary organs affected by amyloid A (AA) amyloidosis in mixed-breed cats. The distribution of amyloid deposits within the kidneys varies among individuals; however, the underlying cause is unknown. This study investigated the association between serum AA (SAA) po...

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Main Authors: Natsumi Kobayashi, Masahiro Kaneda, Mitsuhiro Ikeda, Hirotaka Kondo, Susumu Iwaide, Yoshiyuki Itoh, Miki Hisada, Yuka Kato, Niki Sedghi Masoud, Kohji Nomura, Machie Tsuneyasu, Tomoko Akamine, Tomoaki Murakami
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Amyloidosis
Mass spectrometry
Serum amyloid A
Renal disease
Felis catus
Online Access:https://doi.org/10.1038/s41598-025-07983-7
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https://doi.org/10.1038/s41598-025-07983-7

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